Chapter 58

Early Medical and Surgical Complications After Kidney Transplantation

Wai H. Lim

Wai H. Lim

Department of Renal Medicine, Sir Charles Gairdner Hospital, Perth, Australia

School of Medicine, Discipline of Internal Medicine University of Western Australia, Perth, Australia

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Henry Pleass

Henry Pleass

Specialty of Surgery, Faculty of Medicine and Health, University of Sydney

Centre for Transplant and Renal Research, Westmead Hospital, Sydney, Australia

Department of Surgery, Surgical Research and Education Centre, Westmead Hospital, Sydney, Australia

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First published: 18 November 2022

Summary

Kidney transplantation is the treatment of choice in patients with end-stage kidney disease because it confers a significant survival advantage compared to dialysis treatment. This chapter discusses the short-term medical and surgical complications that can potentially cause allograft failure within one year post kidney transplantation, focusing on the practical approach, investigations, and treatment of these complications. The chapter presents the potential surgical and medical complications occurring in the first 12 months after kidney transplantation. The incidence of ureteric complications after kidney transplantation is estimated at between 2% and 12%, predominantly related to urine leak and obstruction. Acute rejection of the kidney allografts following transplantation continues to be a major impediment to long-term allograft survival. Delayed graft function is a common complication after kidney transplantation, with the highest incidence observed after donation after circulatory death kidney transplants.

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