The comprehensive behavioral (ComB) model focuses on the cycle of antecedents, behaviors, and consequences that maintain body-focused repetitive behaviors (BFRBs). It is postulated that BFRBs occur more frequently in the presence of antecedent triggers that cue the BRFB or urges to engage in the behavior. Overall, experimental studies examining the affective states associated with BRFBs show that these behaviors can be related to diverse emotions and contexts. The stimulus regulation model focuses on the initial onset of BFRBs as an emotion regulation strategy. Recent adaptations to habit reversal therapy (HRT) have begun to be explored to more fully address the emotion regulation functions of BFRBs. A careful functional assessment of the BFRB allows the clinician to better understand the nature, frequency, and contingencies of the behavior, as well as possible cycles of negative and positive reinforcement maintaining the behavior.