Chapter 126

Hereditary Urogenital Cancer Syndromes

Melanie Corbman

Melanie Corbman

Eastern Regional Medical Center, Cancer Treatment Centers of America, Philadelphia, PA, USA

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Eric Fowler

Eric Fowler

Midwestern Regional Medical Center, Cancer Treatment Centers of America, Zion, IL, USA

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First published: 20 June 2014

Summary

Urogenital malignancies are in the cancer spectra of multiple hereditary cancer syndromes. Some diagnoses are strongly associated with inherited risks for cancer, while others are less predictive of a mutation. This chapter utilizes case presentations to emphasize the importance of personal and family histories in cancer genetics risk assessments, explores some of the challenges and uncertainties associated with genetic counseling and testing, and highlights selected controversies in urogenital cancer genetics.

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