Biological Database Integration

Zina Ben Miled

Zina Ben Miled

Indiana University Purdue University Indianapolis, Electrical and Computer Engineering Department, Indianapolis, Indiana

Search for more papers by this author
Yang Liu

Yang Liu

Indiana University Purdue University Indianapolis, Electrical and Computer Engineering Department, Indianapolis, Indiana

Search for more papers by this author
Nianhua Li

Nianhua Li

Indiana University Purdue University Indianapolis, Computer and Information Science, Indianapolis, Indiana

Search for more papers by this author
Omran Bukhres

Omran Bukhres

Indiana University Purdue University Indianapolis, Computer and Information Science, Indianapolis, Indiana

Search for more papers by this author
First published: 14 April 2006

Abstract

Many biomedical databases have rapidly become a central part of knowledge discovery in numerous fields including genomics, proteomics, and drug design. These databases are distributed, heterogeneous, and autonomous. This article by presenting a brief overview of some widely used databases to motivate the need for the integration of the distributed biological databases. Supporting this integration faces numerous challenges including various levels of heterogeneity, limited accessibility and redundancy, or conflicts in the data. These challenges are discussed, and different approaches to addressing these issues are presented. The article also includes a comparison among some integration systems that have been proposed for biological databases.

The full text of this article hosted at iucr.org is unavailable due to technical difficulties.