Chapter 7

Effects of TNF-α on Cardiac Function

First published: 30 August 2007

Summary

This chapter contains section titled:

  • Introduction

  • TNF-á and TNF-á receptors

  • TNF-á and cardiac contractile function

  • Mechanisms of TNF-α induced contractile dysfunction

  • Sphingosine pathway (NO-independent pathway

  • Clinical trials of targeting TNF-á in heart failure patients

  • References

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