Chapter 9

Reversal Agents of Multidrug Resistance Mediated by Multidrug Resistance-Associated Proteins (MRPs)

Ahcène Boumendjel

Ahcène Boumendjel

Université de Grenoble, Grenoble, France

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Anne Florin

Anne Florin

Institut Jean Roget, Université Joseph Fourier, Grenoble, France

Hôpital Michallon de Grenoble, Grenoble, France

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Jean Boutonnat

Jean Boutonnat

Institut Jean Roget, Université Joseph Fourier, Grenoble, France

Hôpital Michallon de Grenoble, Grenoble, France

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First published: 15 June 2009
Citations: 3

Summary

This chapter contains sections titled:

  • Introduction

  • Substrates or drugs extruded by multidrug resistance-associated proteins

  • Methods to evaluate inhibitors of MRP activity

  • MRP modulators

  • Other approaches to MRP Modulation

  • Conclusion

  • References

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