Chapter 5
ABC Proteins and Oncology: Expression, Detection, and Implication of ABC Proteins in Solid Tumors
Jean François Bernaudin,
Anne Fajac,
Jocelyne Fleury-Feith,
Khaldoun Kerrou,
Roger Lacave,
Jean François Bernaudin
Laboratory of Histology and Tumor Biology, University Pierre and Marie Curie Paris VI, Hôpital Tenon APHP, Paris, France
Search for more papers by this authorAnne Fajac
Laboratory of Histology and Tumor Biology, University Pierre and Marie Curie Paris VI, Hôpital Tenon APHP, Paris, France
Search for more papers by this authorJocelyne Fleury-Feith
Laboratory of Histology and Tumor Biology, University Pierre and Marie Curie Paris VI, Hôpital Tenon APHP, Paris, France
Search for more papers by this authorKhaldoun Kerrou
Nuclear Medicine Department, Hôpital Tenon, Paris, France
Search for more papers by this authorRoger Lacave
Laboratory of Histology and Tumor Biology, University Pierre and Marie Curie Paris VI, Hôpital Tenon APHP, Paris, France
Search for more papers by this authorJean François Bernaudin,
Anne Fajac,
Jocelyne Fleury-Feith,
Khaldoun Kerrou,
Roger Lacave,
Jean François Bernaudin
Laboratory of Histology and Tumor Biology, University Pierre and Marie Curie Paris VI, Hôpital Tenon APHP, Paris, France
Search for more papers by this authorAnne Fajac
Laboratory of Histology and Tumor Biology, University Pierre and Marie Curie Paris VI, Hôpital Tenon APHP, Paris, France
Search for more papers by this authorJocelyne Fleury-Feith
Laboratory of Histology and Tumor Biology, University Pierre and Marie Curie Paris VI, Hôpital Tenon APHP, Paris, France
Search for more papers by this authorKhaldoun Kerrou
Nuclear Medicine Department, Hôpital Tenon, Paris, France
Search for more papers by this authorRoger Lacave
Laboratory of Histology and Tumor Biology, University Pierre and Marie Curie Paris VI, Hôpital Tenon APHP, Paris, France
Search for more papers by this authorBook Editor(s):Ahcène Boumendjel, Jean Boutonnat,
Jacques Robert,
Jean Boutonnat
Institut Jean Roget, Université Joseph Fourier, Grenoble, France
Hôpital Michallon de Grenoble, Grenoble, France
Search for more papers by this authorJacques Robert
Institut Bergonié, Université Victor Segalen, Bordeaux, France
Search for more papers by this authorSeries Editor(s): Binghe Wang,
Binghe Wang
Search for more papers by this authorSummary
This chapter contains sections titled:
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Introduction
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Anticancer drugs that are substrates of ABC transporters
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Detection of MDR-related ABC transporters in solid tumor samples
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The cellular and tissue ABC transporter expression in solid tumors
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The host: Pharmacogenetics of ABC transporters and solid tumors
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Clinical relevance of ABC transporter detection in solid tumors
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Conclusion
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References
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