Biodegradation of Polydioxanone
Part 9. Miscellaneous Biopolymers and Biodegradation of Polymers
Dr. Haruo Nishida,
Dr. Haruo Nishida
- [email protected]
- +81-948-22-5706 | Fax: +81-948-22-5706
Kinki University, Molecular Engineering Institute, 11-6 Kayanomori, Iizuka, Fukuoka, Japan, 820-8555
Search for more papers by this authorDr. Haruo Nishida,
Dr. Haruo Nishida
- [email protected]
- +81-948-22-5706 | Fax: +81-948-22-5706
Kinki University, Molecular Engineering Institute, 11-6 Kayanomori, Iizuka, Fukuoka, Japan, 820-8555
Search for more papers by this authorAbstract
- Introduction
- Historical Outline
- Chemical Structure
- Chemical Analysis and Detection
- Functions
- Hydrolyzability
- Depolymerizability
- Physiology
- Biodegradation
- In-vivo Degradation
- Enzymatic Degradation
- Microbial Degradation
- Production
- PDO
- PPDO
- Ring-opening Polymerization
- Enzymatic Polymerization
- Producers, Costs, and World Market
- Applications
- Outlook and Perspectives
- Patents
Polymer/Polymerization
- Akieda, H., Shioya, Y., Kajita, M., Ozu, K. (2001P) Process for producing poly(p-dioxanone), and poly(p-dioxanone) monofilament and process for producing the same. WO 2001019891.
- Baggett, J. M., Horvath, J. W., Wilson, B. W. (1968P) Polymerization of para-dioxanone and derivatives. US Patent 3,391,126.
- Bezwada, R. S., Shalaby, S. W., Newman, H., Jr., Kafrawy, A. (1987) Crystalline copolymers of p-dioxanone and lactide and surgical devices made therefrom. US Patent 4,643,191.
- Bezwada, R. S., Kronenthal, R. L. (1991P) Random copolymers of p-dioxanone, lactide and/or glycolide as coating polymers for surgical filaments. European Patent 0,411,545 A1.
- Cox, E. F., Hostettler, F. (1962Pa-i) Polymerization of cyclic esters. US Patent 3,021,309-17.
- Cox, E. F., Hostettler, F. (1965P) Polymerization of cyclic esters. US Patent 3,190,858.
- Critchfield, F. E., Lundberg, R. D. (1972Pa) Production of relatively high molecular weight polymers of cyclic esters. Canadian Patent 900091.
- Critchfield, F. E., Lundberg, R. D. (1972Pb) Method for the manufacture of relatively high molecular weight polymers of cyclic esters. Canadian Patent 900093.
- Forschner, T. C. (1997P) Method for preparing poly-p-dioxanone polymer. WO 97/21753.
- Forschner, T. C., Gwyn, D. E., Veith, C. A. (1998P) Method for preparing poly-p-dioxanone polymer in the melt. WO 98/08887.
- Nishida, H., Yamashita, M. (2000Pa) Metal-free p-dioxanone polymers, their enzymatic preparation, and medical goods or sanitary products therefrom. Japanese Patent 2000044658 A2.
- Schultz, H. S. (1962Pa) Polymers of 2-p-dioxanone and method for making same. US Patent 3,063,967.
- Schultz, H. S. (1962Pb) Polymers of 2-p-dioxanone. US Patent 3,063,968.
- Shalaby, S. W., Koelmel, D. F. (1984P) Copolymers of p-dioxanone and 2,5-morpholinediones and surgical devices formed therefrom having accelerated absorption characteristics. US Patent 4,441,496.
- Snapp, T. C., Blood, A. E. (1972P) Method of preparing 2-p-dioxanone polymers. US Patent 3,645,941.
- Weipert, E. A. (1962P) Polymerization of 2-p-dioxanone with sulfuric acid. US Patent 3,020,289.
Processing
- Broyer, E (1991P) Thermal treatment of thermoplastic filaments. European Patent 0,415,783 A2.
- Gertzman, A. A., Thompson, D. R. (1983P) Formteile für chirurgische Zwecke und Verfahren zu ihrer Herstellung. DE 3227828 A1.
Alloys/Composites
- Borysko, E. (1984P) Sucrose and/or lactose nucleating agents for the crystallization of polydioxanone. US Patent 4,444,927.
- Brizzolara, N. S., Lanzilotti, M. G., Lawter, J. R. (1990P) Method for the treatment of periodontal disease by sustained delivery of a therapeutic agent to the periodontal pocket, composition of matter therefor and apparatus for the administration thereof. European Patent 0,374,531 A2.
- Doddi, N., Versfelt, C. C., Wasserman, D. (1977Pa) Arzneimittel mit Depotwirkung. DE 2821949 A1.
- Farr, M. P., Lincoln, D. M., Moyers, C. G. (1997P) Stabilized dioxanone polymers. European Patent 0,763,559 A2.
- Koelmel, D. F., Shalaby, S. W., Jamiolkowski, D. D. (1986P) Compatible blends of poly(p-dioxanone) and poly(alkylene phenylene-bis-oxyacetate) and absorbable surgical devices made therefrom. European Patent 0,185,467,A2.
- Nishida, H., Yamashita, M. (1998Pa) Biodegradable poly(p-dioxanone) compositions with improved stability and their moldings. Japanese Patent 10259297 A2.
- Walter, E. R., Koleske, J. V. (1972P) Crystalline polymer alloys comprising a polymer from a cyclic ester and an alkene polymer. US Patent 3,632,687.
Applications
- Bezwada, R. S., Hunter, A. W. (1994P) Castor oil polymers for needle coatings. European Patent 0,610,086 A2.
- Chen, C., Weaver, G., Kindberg, R., Carroll, K., Spengler, R. (1992P) Polymeric endoscopic ligature. European Patent 0,477,020 A1.
- Cooper, K., Chen, C. C., Scopelianos, A. G. (1996P) Hard tissue bone cements and substitutes. European Patent 0,714,666 A1.
- Doddi, N., Versfelt, C. C. (1977Pb) Synthetic absorbable surgical devices of poly-dioxanone. US Patent 4,052,988.
- Dorband, G. C., Liland, A., Menezes, E. V., Steinheuser, P., Popadiuk, N., Failla, S. J. (1986P) Surgical fastening device and method for manufacture. European Patent 0,202,090 A2.
- Dunn, R. L., Tipton, A. J., Southard, G. L., Rogers, J. A. (1991P) Biodegradable system for regenerating the periodontium. WO 91/01126.
- Jamiolkowski, D. D., Newman, H. D., Jr., Datta, A., Tandon, R., Chen, I-J., Suryadevara, J., Canterberry, B. A., Fitzgerald, S. E. (1996P) Medical devices containing high inherent viscosity poly(p-dioxanone). European Patent 0,691,359 A2.
- Lipinsky, E. S., Browning, J. D. (1995P) Degradable polydioxanone-based materials. WO 95/09164.
- Nagashima, M., Yamashita, M., Nishida, H. (2001P) Biodegradable heat-sealable p-dioxanone polymer bags and their manufacture. Japanese Patent 2001018983.
- Nishida, H. (2000Pb) Nonporous moisture-permeable films with excellent biodegradability. Japanese Patent 2000017066 A2.
- Nishida, H., Nagashima, M., Ohura, M. (2001P) Biodegradable p-dioxanone polymer porous film. Japanese Patent 2001002810.
- Potts, E. J. (1983P) Disposable articles coated with degradable water insoluble polymers. US Patent 4,372,311.
- Potts, J. E. (1985P) Disposable articles coated with degradable water insoluble polymers. US Patent 4,503,098.
- Prisell, P., Norstedt, G. (1990P) Pharmaceutical preparation. WO 90/05522.
- Schechtman, L. A. (1991P) Disposable sanitary articles. WO 91/10004; US Patent 5,026,589.
- Suzuki, K., Fukuda, K. (1993P) Minute polymeric rod for preventing tear flow into the lacrimal duct. Japanese Patent 05092015 A2.
- Yamashita, M., Hattori, N., Nishida, H. (1999P) Biodegradable poly(p-dioxanone) compositions and its moldings as hygienic products. Japanese Patent 11005893 A2.
- Yamashita, M., Nishida, H. (2000Pa) Biodegradable heat-shrinkable p-dioxanone polymer films and their manufacture. Japanese Patent 2000301608.
Biodegradation/Recycling
- Nishida, H., Yamashita, M., Hattori, N. (1998Pb) Methods for the preparation of 2-p-dioxanone. Japanese Patent 10045744.
- Nishida, H., Hattori, N., Yamashita, M (1998Pc) Methods for preparation of 2-p-dioxanone by thermolysis. Japanese Patent 10045745.
- Nishida, H., Konno, M. (2000Pc) Treatment of aliphatic polyether-ester polymers. Japanese Patent 2000103843.
Monomer Production
- Forschner, T. C. (1994P) process for preparing para-dioxanones. US Patent 5,310,945.
- Gresham, W. F. (1944P) Preparation of organic esters. US Patent 2,364,438.
- Guest, H. R., Kiff, B. W. (1959P) Process for the production of 2-paradioxanone. US Patent 2,900,395.
- Hattori, N. (1998P) Preparation of 2-p-dioxanone as monomers. Japanese Patent 10120675 A2.
- Mayhew, R. L., Glickman, S. A. (1964P) Preparation of 2-p-dioxanone by dehydrogenating diethylene glycol in the presence of added hydrogen. US Patent 3,119,840.
- McNamee, R. W., Blair, C. M. (1938P) Process for the production of 2-p-dioxanone. US Patent 2,142,033.
- Nakatani, S., Matsumoto, T., Nakahara, Y., Akieda, H., Ishitoku, T. (2001P) Process for the preparation of purified salts of (2-hydroxyethoxy)acetic acid. European Patent 1,138,664 A2.
- Suzuki, S. (1978P) Process for preparing 1,4-dioxan-2-ones. US Patent 4,070,375.
- Souma, Y. (1991P) Process for producing lactones. US Patent 4,990,629.
- Yamashita, M., Nagashima, M., Nishida, H. (2000Pb) Manufacture of 2-p-dioxanones from diethylene glycols. Japanese Patent 2000351775 A2.
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