Biodegradation of Polyanhydrides

Part 9. Miscellaneous Biopolymers and Biodegradation of Polymers
Dr. Neeraj Kumar

Dr. Neeraj Kumar

The Hebrew University of Jerusalem, Department of Medicinal Chemistry and Natural Products, School of Pharmacy, Jerusalem, Israel, 91120

Search for more papers by this author
Dr. Majeti N. V. Ravikumar

Dr. Majeti N. V. Ravikumar

University of Kentucky Medical Center, Department of Preventive Medicine and Environmental Health, 354 Health Sciences Research Building, Lexington, Kentucky, USA, 40536

Search for more papers by this author
Raia Slivniak

Raia Slivniak

The Hebrew University of Jerusalem, Department of Medicinal Chemistry and Natural Products, School of Pharmacy, Jerusalem, Israel, 91120

Search for more papers by this author
Ms. Michal Y. Krasko

Ms. Michal Y. Krasko

The Hebrew University of Jerusalem, Department of Medicinal Chemistry and Natural Products, School of Pharmacy, Jerusalem, Israel, 91120

Search for more papers by this author
Prof. Dr. Abraham J. Domb

Prof. Dr. Abraham J. Domb

The Hebrew University of Jerusalem, Department of Medicinal Chemistry and Natural Products, School of Pharmacy, Jerusalem, Israel, 91120

Search for more papers by this author
First published: 15 January 2005

Abstract

  • Introduction
    • Degradation: A Real Meaning
    • Mechanisms Involved in Degradation
  • Historical Outline
  • Polymer Erosion
    • Changes in Polymer Structure During Erosion
      • Morphological Changes
      • Changes in Composition and Physico-chemical Properties
      • Release of Monomers and Drugs
    • Factors Affecting Degradation
      • Water Uptake
      • Crystallinity and Molecular Weight
      • pH
      • Copolymer Composition
      • Enzymatic Degradation
  • Synthesis
  • Structures
  • Surface Analysis
  • Polyanhydride Degradation: In-vitro and In-vivo Approaches
    • In-vitro Degradation and Drug Release
    • In-vivo Degradation and Drug Release
  • Modeling of Polymer Erosion
  • Production of Polyanhydrides
    • World Market
    • Applications
    • Patents
  • Outlook and Perspectives

The full text of this article hosted at iucr.org is unavailable due to technical difficulties.