Communication
Enantioselective Intramolecular [2+2]-Photocycloaddition Reactions in Solution
First published: 04 July 2000
Citations: 121
This project was supported by the Deutsche Forschungsgemeinschaft (Ba 1372-4/1 and -4/2) and by the Fonds der Chemischen Industrie. We would like to thank Stefan Sieber (undergraduate research participant) for skillful technical assistance.
Crystal structure determination
Graphical Abstract
Hydrogen bonds facilitate the coordination of prochiral 2-quinolones, such as 1, to the chiral host 2. As a result, the intramolecular [2+2]-photocycloaddition reaction which yields cyclobutanes, such as 3, proceeds with high enantioselectivity (up to 93 % ee). The host can be separated from the products and is recovered almost quantitatively.
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