Vitamins, 10. Folic Acid
This is not the most recent version, view other versions
Most recent
Vitamins, 12. Vitamin B9
Peter Mair, Szabolcs Péter, René T. Stemmler, Christof Wehrli, Bernd-Jürgen Weimann, Urs Hengartner, Antoine Saizieu,
This version
Vitamins, 10. Folic Acid
Vitamins
Manfred Eggersdorfer, Geo Adam, Michael John, Wolfgang Hähnlein, Ludvik Labler, Kai-U. Baldenius, Linda von dem Bussche-Hünnefeld, Eckhard Hilgemann, Peter Hoppe, Rainer Stürmer, Fritz Weber, August Rüttimann, Gérard Moine, Hans-Peter Hohmann, Roland Kurth, Joachim Paust, Wolfgang Hähnlein, Horst Pauling, Bernd–Jürgen Weimann, Bruno Kaesler, Bernd Oster, Ulrich Fechtel, Klaus Kaiser, Bernd de Potzolli, Michael Casutt, Thomas Koppe, Michael Schwarz, Bernd-Jürgen Weimann, Urs Hengartner, Antoine de Saizieu, Christof Wehrli, René Blum,
Bernd-Jürgen Weimann,
Urs Hengartner, Antoine de Saizieu,
Christof Wehrli,
Bernd-Jürgen Weimann
F. Hoffmann-La Roche Ltd, Basel, Switzerland
Search for more papers by this authorAntoine de Saizieu
F. Hoffmann-La Roche Ltd, Basel, Switzerland
Search for more papers by this authorBernd-Jürgen Weimann,
Urs Hengartner, Antoine de Saizieu,
Christof Wehrli,
Bernd-Jürgen Weimann
F. Hoffmann-La Roche Ltd, Basel, Switzerland
Search for more papers by this authorAntoine de Saizieu
F. Hoffmann-La Roche Ltd, Basel, Switzerland
Search for more papers by this authorAbstract
The article contains sections titled:
1. |
Introduction |
2. |
Historical Notes |
3. |
Properties |
4. |
Content in Food and Bioavailability |
5. |
Biosynthesis |
6. |
Chemical Synthesis |
7. |
Metabolism and Biochemical Functions |
8. |
Nutritional Requirements and Medical Use |
9. |
Analysis |
10. |
Economic Aspects |
Specific References
- 1 IUPAC-IUB Joint Commission on Biochemcial Nomenclature (JCBN): “Nomenclature and Symbols for Folic Acid and Related Compounds,” Recommendations 1986, Eur. J. Biochem. 168 (1987) 251–253; Pure Appl. Chem. 59 (1987) 834–836.
- 2 L. Wills, P. W. Clutterbuck, P. D. F. Evans, Biochem. J. 31 (1937) 2136–2147.
- 3 A. G. Hogan, E. M. Parrott, J. Biol. Chem. 132 (1940) 507–517.
- 4 E. E. Snell, W. H. Peterson, J. Bacteriol. 39 (1940) 273–285.
- 5 H. K. Mitchell, E. E. Snell, R. J. Williams, J. Am. Chem. Soc. 63 (1941) 2284.
- 6 S. B. Binkley et al., Science (Washington D.C. 1883) 100 (1944) 36–37.
- 7 J. J. Pfiffner, D. G. Calkins, E. S. Bloom, L. B. O'Dell, J. Am. Chem. Soc. 68 (1946) 1392.
- 8 R. B. Angier et al., Science (Washington D.C. 1883) 103 (1946) 667–669.
- 9 A. D. Welch, Perspect. Biol. Med. 27 (1983) 64–75.
- 10 R. L. Blakley, S. J. Benkovic (eds.): Folates and Pterins, vols. 1 and 2, J. Wiley & Sons, New York 1984 /1985.
- 11 O. Isler, G. Brubacher in O. Isler, G. Brubacher, S. Gishla, B. Kräutler (eds.): Vitamine II, Thieme Verlag, Stuttgart–New York 1988, pp. 264–308.
- 12 T. Maruyama, T. Shiota, C. L. Krumdieck, Anal. Biochem. 84 (1978) 277–295.
- 13 L. B. Bailey (ed.): Folate in Health and Disease, M. Dekker Inc., New York–Basel–Hong Kong 1995.
- 14 P. A. Charlton et al., J. Chem. Soc., Perkin Trans. 1 1985, 1349–1353.
- 15 C. M. Tatum, M. G. Fernald, J. P. Schimel, Anal. Biochem. 103 (1980) 255–257.
- 16 J. A. Blair, K. J. Saunders, Anal. Biochem. 34 (1970) 376–381.
- 17 C. Zarow, A. M. Pellino, P. V. Danenberg, Prep. Biochem. 12 (1983) 381–393.
- 18 J. E. Baggott, C. L. Krumdieck, Biochemistry 18 (1979) 1036–1041.
- 19 E. Khalifa, A. N. Ganguly, J. H. Bieri, M. Viscontini, Helv. Chim. Acta 63 (1980) 2554–2558.
- 20 P. Stover, V. Schirch, Anal. Biochem. 202 (1992) 82–88.
- 21 T. Eguchi et al., Biosci. Biotech. Biochem. 56 (1992) 701–703.
- 22 D. B. Cosulich, J. M. Smith, H. P. Broquist, J. Am. Chem. Soc. 74 (1952) 4215–4216.
- 23 W. Friedrich: Handbuch der Vitamine, Urban & Schwarzenberg, München–Wien–Baltimore 1987, pp. 398–485.
- 24 B. Bötticher, R. Kluthe in K. Pietrzik (ed.): Folsäure-Mangel, W. Zuckschwerdt Verlag, München 1987, pp. 15–24.
- 25 T. Brody in L. J. Machlin (ed.): Handbook of Vitamins, M. Dekker Inc., New York–Basel–Hong Kong 1991, pp. 453–489.
- 26 L. B. Bailey in L. B. Bailey (ed.): Folate in Health and Disease, M. Dekker Inc., New York–Basel–Hong Kong 1995, pp. 123–151.
- 27 K. H. Bässler, E. Grühn, D. Loew, K. Pietrzik: Vitamin-Lexikon, G. Fischer Verlag, Stuttgart –Jena–New York 1992, pp. 127–154.
- 28 J. Leichter, A. F. Landymore, C. L. Krumdieck, Am. J. Clin. Nutr. 32 (1979) 92–95.
- 29 S. P. Rothenberg, M. P. Iqbal, M. Da Costa, Anal. Biochem. 103 (1980) 152–156.
- 30 J. F. Gregory, Adv. Food Nutr. Res. 33 (1989) 1–101.
- 31 H. E. Sauberlich et al., Am. J. Clin. Nutr. 46 (1987) 1016–1028.
- 32 J. F. Gregory in L. B. Bailey (ed.): Folate in Health and Disease, M. Dekker Inc., New York–Basel–Hong Kong 1995, pp. 195–235.
- 33 G. M. Brown, H. Williamson, Adv. Enzymol. Relat. Areas Mol. Biol. 53 (1982) 345–381.
- 34 G. M. Brown, H. Williamson in F. C. Neidhardt (ed.): Escherichia coli and Salmonella typhymurium, vol. 1, American Society for Microbiology, Washington, D.C. 1987, pp. 521–538.
- 35 A. de Saizieu, P. Vankan, A. P. G. M. van Loon, Biochem. J. 306 (1995) 371–377.
- 36 Y. Suzuki, G. M. Brown, J. Biol. Chem. 249 (1974) 2405–2410.
- 37 J. Toy, A. L. Bognar, J. Biol. Chem. 265 (1990) 2492–2499.
- 38 J. Slock et al., J. Bacteriol. 172 (1990) 7211–7226.
- 39 S. A. Lacks, B. Greenberg, P. Lopez, J. Bacteriol. 177 (1995) 66–74.
- 40 P. Babitzke, P. Gollnick, C. Yanofsky, J. Bacteriol. 174 (1992) 2059–2064.
- 41
P. S. Margolis,
A. Dirks,
R. Losick,
J. Bacteriol.
175
(1993)
528–540.
10.1128/jb.175.2.528-540.1993 Google Scholar
- 42 C. W. Waller et al., J. Am. Chem. Soc. 70 (1948) 19–22.
- 43 F. Weygand, V. Schmied-Kowarzik, Chem. Ber. 82 (1949) 333–336.
- 44 S. Uyeo, S. Mizukami, T. Kubota, S. Takagi, J. Am. Chem. Soc. 72 (1950) 5339–5340.
- 45 P. Karrer, R. Schwyzer, Helv. Chim. Acta 31 (1948) 777–782.
- 46 F. Hoffmann-La Roche, EP-A 608 693 A2, 1994 (C. Wehrli).
- 47 M. Sletzinger et al., J. Am. Chem. Soc. 77 (1955) 6365–6367.
- 48 E. C. Taylor, R. N. Henrie, R. C. Portnoy, J. Org. Chem. 43 (1978) 736–737.
- 49 J. H. Bieri, M. Viscontini, Helv. Chim. Acta 56 (1973) 2905–2911. E. Khalifa, P. K. Sengupta, J. H. Bieri, M. Viscontini, Helv. Chim. Acta 59 (1976) 242–247.
- 50 C. M. Baugh, C. L. Krumdieck, H. J. Baker, C. E. Butterworth, J. Nutr. 105 (1975) 80–89.
- 51 T. T. Y. Wang, A. M. Reisenauer, C. H. Halsted, J. Nutr. 115 (1985) 814–819.
- 52 A. M. Reisenauer, C. L. Krumdieck, C. H. Halsted, Science (Washington D.C. 1883) 198 (1977) 196–197.
- 53 C. J. Chandler, T. T. Y. Wang, C. H. Halsted, J. Biol. Chem. 261 (1986) 928–933.
- 54 J. Zimmerman, Z. Gilula, J. Selhub, I. H. Rosenberg, Int. J. Vitam. Nutr. Res. 59 (1989) 151–156.
- 55 J. Zimmerman, J. Selhub, I. H. Rosenberg, Am. J. Clin. Nutr. 46 (1987) 518–522.
- 56 J. Kiil, M. Jaegerstad, L. Elsborg, Int. J. Vitam. Nutr. Res. 49 (1979) 296–306.
- 57 V. Herbert, K. C. Das in M. E. Shils, J. A. Olson, M. Shike (eds.): Modern Nutrition in Health and Disease, 8th ed., Lea & Fabiger, Philadelphia 1993, pp. 402–425.
- 58 C. Wagner, Annu. Rev. Nutr. 2 (1982) 229–248.
- 59 G. B. Henderson, Annu. Rev. Nutr. 10 (1990) 319 –335.
- 60 J. J. McGuire, J. R. Bertino, Mol. Cell. Biochem. 38 (1981) 19–48.
- 61 J. J. McGuire, J. K. Coward in R. L. Blakley, S. J. Benkovic (eds.): Folates and Pterins, vol. 1, J. Wiley & Sons, New York 1984, pp. 135–190.
- 62 R. G. Moran, P. D. Colman, Anal. Biochem. 140 (1984) 326–342.
- 63 C. Wagner in L. B. Bailey (ed.): Folate in Health and Disease, M. Dekker Inc., New York–Basel –Hong Kong 1995, pp. 23–42.
- 64 V. Herbert, Am. J. Clin. Nutr. 21 (1968) 743–752.
- 65 V. Herbert et al., Trans. Assoc. Am. Physicians 97 (1984) 161–171.
- 66 Recommended Dietary Allowances, 10th ed., National Academy Press, Washington 1989.
- 67 C. J. Allegra et al., N. Engl. J. Med. 317 (1987) 978 –985.
- 68 J. Jolivet et al., N. Engl. J. Med. 309 (1983) 1094 –1104.
- 69 W. E. Evans et al., N. Engl. J. Med. 314 (1986) 471 –477.
- 70 D. C. Heimburger et al., J. Am. Med. Assoc. 259 (1988) 1525–1530.
- 71 S. H. Mudd et al., Biochem. Biophys. Res. Commun. 46 (1972) 905–912.
- 72 J. B. Ubbink, W. J. H. Vermaak, A. van der Merve, P. J. Becker, Am. J. Clin. Nutr. 57 (1993) 47–53.
- 73 H. Refsum, P. M. Ueland, S. Kvinnsland, Cancer Res. 46 (1986) 5385–5391.
- 74 E. H. Broxson et al., Cancer Res. 49 (1989) 5879 –5883.
- 75 D. W. Jacobsen, V. J. Gatautis, R. Green, Clin. Chem. (Winston Salem N.C.) 40 (1994) 873–881.
- 76 A. Andersson et al., Eur. J. Clin. Invest. 22 (1992) 79–87.
- 77 J. Mulinare, J. F. Cordero, J. D. Erickson, R. J. Berry, J. Am. Med. Assoc. 260 (1988) 3141–3145.
- 78 A. F. Czeisal, J. Dudas, N. Engl. J. Med. 327 (1992) 1832–1835.
- 79 MRC Vitamin Study Research Group: “Prevention of Neural Tube Defects: Results of the Medical Research Council Vitamin Study,” Lancet 1991, no. 338, 131–137.
- 80 R. W. Smithells et al., Lancet 1983 vol. I, 1027 –1031.
- 81 Centres of Disease Control and Prevention: “Recommendations for the Use of Folic Acid to Reduce the Number of Cases of Spina Bifida and Other Neural Tube Defects,” J. Am. Med. Soc. 269 (1993) 1233–1238.
- 82 Expert Advisory Group to U.K. Department of Health: Folic Acid and the Prevention of Neural Tube Defects, Department of Health, London 1992, pp. 1–33.
- 83 C. E. Butterworth, T. Tamura, Am. J. Clin. Nutr. 50 (1989) 353–358.
- 84 A. Hanck in: Spektrum Vitamine, vol. 42, Aesopus Verlag, Zug 1986, pp. 81–85.
- 85 Nutrient Requirements of Poultry, 9th revised ed., NRC 1994, Nutrient Requirements of Swine, 9th revised ed. 1988, NRC, National Academy Press, Washington, D.C.
- 86 Arbeitsgemeinschaft für Wirkstoffe in der Tierernährung e. V. (AWT): Vitamine in der Tierernährung, Bonn 1991.
- 87 C. L. Krumdieck, T. Tamura, I. Eto, Vitam. Horm. (N.Y.) 40 (1983) 45–104.
- 88
G. Brubacher,
W. Müller-Mulot,
D. A. T. Southgate:
Methods for Determination of Vitamins in Food,
Elsevier Appl. Sci. Publ.,
London–New York
1985,
pp. 158–159.
10.1007/978-94-009-4944-7_14 Google Scholar
- 89 D. B. McCormick, L. D. Wright (eds.), Methods Enzymol. 66E (1980) 429–727.
- 90 L. V. Fenys, K. D. Thakker, V. D. Reif, L. T. Grady, J. Pharm. Sci. 71 (1982) 1242–1246.
- 91 H. E. Sauberlich, Annu. Rev. Nutr. 4 (1984) 377 –407.
- 92 S. D. Wilson, D. W. Horne, Anal. Biochem. 142 (1984) 529–535.
- 93 S. A. Kashani, B. A. Cooper, Anal. Biochem. 146 (1985) 40–47.
- 94
J. Kas,
J. Cerna,
Methods Enzymol.
66E
(1980)
443–451.
10.1016/0076-6879(80)66487-8 Google Scholar
Further Reading
- G. Ball: Vitamins, 2nd ed., Wiley, Hoboken 2010.
-
John H. Block:
Vitamins, Survey,
Kirk Othmer Encyclopedia of Chemical Technology,
5th ed., vol. 25,
p. 781–808,
John Wiley & Sons,
Hoboken, NJ,
2007,
online DOI: 10.1002/0471238961.1921182219031520.a01.pub2.
10.1002/0471238961.1921182219031520.a01.pub2 Google Scholar
- G. F. Combs: The Vitamins, 3rd ed., Academic Press, 2007.
-
M. F. Holick:
Vitamin D,
2nd ed.,
Humana,
London
2010.
10.1007/978-1-60327-303-9 Google Scholar
- G. W. A. Milne, M. Delander: Vitamin D Handbook, Wiley-Interscience, Hoboken 2008.
-
J. Zempleni,
R. B. Rucker,
J. W. Suttie,
D. B. McCormick:
Handbook of Vitamins,
4th ed.,
CRC Press,
Boca Raton, FL
2007.
10.1201/9781420005806 Google Scholar