Volume 23, Issue 5 pp. 322-325
Original Article

Fine-needle aspiration diagnosis of Kaposi's sarcoma in a developing country

Elena Gamborino M.D.

Elena Gamborino M.D.

Institute of Molecular Pathology and Immunology (IPATIMUP), of the University of Porto, Porto, Portugal

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Carla Carrilho M.D., Ms.C.

Carla Carrilho M.D., Ms.C.

Department of Pathology, Hospital Central of Maputo, Medical Faculty of Maputo, Maputo, Mozambique

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Josefo Ferro M.D., Ms.C.

Josefo Ferro M.D., Ms.C.

Department of Pathology, Hospital Central of Maputo, Medical Faculty of Maputo, Maputo, Mozambique

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Marian S. Khan M.D.

Marian S. Khan M.D.

Department of Pathology, Hospital Central of Maputo, Medical Faculty of Maputo, Maputo, Mozambique

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Carlos Garcia M.D.

Carlos Garcia M.D.

Department of Pathology, Hospital Central of Maputo, Medical Faculty of Maputo, Maputo, Mozambique

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Martha C. Suarez M.D.

Martha C. Suarez M.D.

Department of Pathology, Hospital Central of Maputo, Medical Faculty of Maputo, Maputo, Mozambique

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Hideky Yokoyama M.D.

Hideky Yokoyama M.D.

Department of Pathology, Hospital Central of Maputo, Medical Faculty of Maputo, Maputo, Mozambique

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Fernando C. Schmitt M.D., Ph.D., M.I.A.C.

Corresponding Author

Fernando C. Schmitt M.D., Ph.D., M.I.A.C.

Institute of Molecular Pathology and Immunology (IPATIMUP), of the University of Porto, Porto, Portugal

IPATIMUP, Rua Roberto Frias s/no, 4200 Porto, PortugalSearch for more papers by this author

Abstract

Fine-needle aspiration (FNA) cytology was performed on 15 patients with peripheral lymphadenopathy and/or skin lesions referred to the Department of Pathology of the Hospital Central of Maputo, Maputo, Mozambique. Epitrochlear lymph nodes were the most frequently aspirated site. All aspirates allowed diagnoses of Kaposi's sarcoma (KS). Smears contained loosely cohesive clusters of bland spindle cells, with a radial arrangement and nuclear crush artifacts. These diagnostic clues have not been described in other spindle-cell intranodal lesions that should be considered in differential diagnoses. Taking into consideration the high prevalence of AIDS and limited resources for diagnosis in Africa, FNA cytology appears to be a useful method for the diagnosis of KS in developing countries, reducing the necessity for surgical lymph node excision. Diagn. Cytopathol. 200;23:322–325. © 2000 Wiley-Liss, Inc.

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