Polyhydroxyalkanoates: Microbial Synthesis and Applications

Guo-Qiang Chen

Guo-Qiang Chen

Center for Synthetic and Systems Biology, Tsinghua University, Beijing, People's Republic of China

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Xiaoran Jiang

Xiaoran Jiang

Center for Synthetic and Systems Biology, Tsinghua University, Beijing, People's Republic of China

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Hui Yao

Hui Yao

Center for Synthetic and Systems Biology, Tsinghua University, Beijing, People's Republic of China

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Li Lv

Li Lv

Center for Synthetic and Systems Biology, Tsinghua University, Beijing, People's Republic of China

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Tian Li

Tian Li

Center for Synthetic and Systems Biology, Tsinghua University, Beijing, People's Republic of China

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Xiangbin Chen

Xiangbin Chen

Center for Synthetic and Systems Biology, Tsinghua University, Beijing, People's Republic of China

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First published: 15 August 2017

Abstract

Polyhydroxyalkanoates (PHAs), an increasingly diverse biopolyesters, have been used for various applications including high and low value ones. High value applications include medical implants, drug delivery, and smart materials, whereas low value applications include environmentally friendly packaging materials, biofuels, and matrices for sustainable fertilizer and/or pesticide release. Various technologies have been utilized to tailor PHAs with specific structures and properties. Cost-effective seawater-based technology allows PHA production to be conducted in unsterile and continuous conditions using seawater instead of fresh water, which leads to fresh water and energy saving. All these advances have reduced the PHAs production cost significantly. Future PHAs are expected to be more competitive economically and provide additional functionalities for high value applications.

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