m-Chloroperbenzoic Acid
A. Somasekar Rao,
H. Rama Mohan,
André Charette,
A. Somasekar Rao
Indian Institute of Chemical Technology, Hyderabad, India
Search for more papers by this authorH. Rama Mohan
Indian Institute of Chemical Technology, Hyderabad, India
Search for more papers by this authorA. Somasekar Rao,
H. Rama Mohan,
André Charette,
A. Somasekar Rao
Indian Institute of Chemical Technology, Hyderabad, India
Search for more papers by this authorH. Rama Mohan
Indian Institute of Chemical Technology, Hyderabad, India
Search for more papers by this authorAbstract
[937-14-4] C7H5ClO3 (MW 172.57)
InChI = 1S/C7H5ClO3/c8-6-3-1-2-5(4-6)7(9)11-10/h1-4,10H
InChIKey = NHQDETIJWKXCTC-UHFFFAOYSA-N
(electrophilic reagent capable of reacting with many functional groups; delivers oxygen to alkenes, sulfides, selenides, and amines)
Alternate Name: m-CPBA; MCPBA.
Physical Data: mp 92–94 °C.
Solubility: soluble in CH2Cl2, CHCl3, 1,2-dichloroethane, ethyl acetate, benzene, and ether; slightly soluble in hexane; insoluble in H2O.
Form Supplied in: white powder, available with purity of 50%, 85%, and 98% (the rest is 3-chlorobenzoic acid and water).
Analysis of Reagent Purity: iodometry.2
Purification commercial material (purity 85%) is washed with a phosphate buffer of pH 7.5 and dried under reduced pressure to furnish reagent with purity >99%.3
Handling, Storage, and Precautions: pure m-CPBA is shock sensitive and can deflagrate;4 potentially explosive, and care is required while carrying out the reactions and during workup.5 Store in polyethylene containers under refrigeration.
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