Extract from Sickingia williamsii Reduces Morphine Withdrawal in vitro
Abstract
The present study examined the effect of an extract from Sickingia williamsii Standl. (Rubiaceae) on morphine withdrawal in vitro. The extract of S. williamsii (50–100–250 μg\mL organ bath) significantly and in a concentration dependent manner reduced the morphine withdrawal. The results of the present study suggest that this extract may be a potential antiaddictive agent.