Anionic polymerization of alkyl cyanoacrylates: In vitro model studies for in vivo applications
Dhirendra Katti
Organic Coatings and Polymers Division, Indian Institute of Chemical Technology, Hyderabad 500007, India
Search for more papers by this authorCorresponding Author
N. Krishnamurti
Organic Coatings and Polymers Division, Indian Institute of Chemical Technology, Hyderabad 500007, India
Organic Coatings and Polymers Division, Indian Institute of Chemical Technology, Hyderabad 500007, India===Search for more papers by this authorDhirendra Katti
Organic Coatings and Polymers Division, Indian Institute of Chemical Technology, Hyderabad 500007, India
Search for more papers by this authorCorresponding Author
N. Krishnamurti
Organic Coatings and Polymers Division, Indian Institute of Chemical Technology, Hyderabad 500007, India
Organic Coatings and Polymers Division, Indian Institute of Chemical Technology, Hyderabad 500007, India===Search for more papers by this authorAbstract
Alkyl cyanoacrylates were polymerized anionically in water medium at different levels of pH. The effect of pH on the molecular weight and softening points of the polymers was studied. Alkyl cyanoacrylates were also polymerized in suspension by using the combination of methanol–water, and also by using different catalysts such as triethylamine, diazabicyclooctane, and diazabicycloundecane. The poly(cyanoacrylates) thus obtained were characterised by infrared and nuclear magnetic resonance spectroscopy. The molecular weight, molecular weight distribution, and the softening points of the polymers were determined. These studies would help in more effective usage of cyanoacrylates as bioadhesives under varied physiological conditions. © 1999 John Wiley & Sons, Inc. J Appl Polym Sci 74: 336–344, 1999
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