Volume 21, Issue 10 pp. 1341-1343

Short Report

Axonal and demyelinating neuropathy with reversible proximal conduction block, an unusual feature of vitamin B12 deficiency

Asmahan F. Al-Shubaili MRCP,

Asmahan F. Al-Shubaili MRCP

Department of Neurology and Clinical Neurophysiology, Ibn Sina Hospital, PO Box 25427, Safat 13115, Kuwait

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Sameer A. Farah MRCP,

Corresponding Author

Sameer A. Farah MRCP

Department of Neurology and Clinical Neurophysiology, Ibn Sina Hospital, PO Box 25427, Safat 13115, Kuwait

Department of Neurology and Clinical Neurophysiology, Ibn Sina Hospital, PO Box 25427, Safat 13115, KuwaitSearch for more papers by this author

Jassim M. Hussein MRCP,

Jassim M. Hussein MRCP

Department of Neurology and Clinical Neurophysiology, Ibn Sina Hospital, PO Box 25427, Safat 13115, Kuwait

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Joze V. Trontelj MD, DSc,

Joze V. Trontelj MD, DSc

Institute of Clinical Neurophysiology, University Medical Center, Ljubljana, Slovenia

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Adnan J. Khuraibet MSc, DSc,

Adnan J. Khuraibet MSc, DSc

Department of Neurology and Clinical Neurophysiology, Ibn Sina Hospital, PO Box 25427, Safat 13115, Kuwait

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Asmahan F. Al-Shubaili MRCP,

Asmahan F. Al-Shubaili MRCP

Department of Neurology and Clinical Neurophysiology, Ibn Sina Hospital, PO Box 25427, Safat 13115, Kuwait

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Sameer A. Farah MRCP,

Corresponding Author

Sameer A. Farah MRCP

Department of Neurology and Clinical Neurophysiology, Ibn Sina Hospital, PO Box 25427, Safat 13115, Kuwait

Department of Neurology and Clinical Neurophysiology, Ibn Sina Hospital, PO Box 25427, Safat 13115, KuwaitSearch for more papers by this author

Jassim M. Hussein MRCP,

Jassim M. Hussein MRCP

Department of Neurology and Clinical Neurophysiology, Ibn Sina Hospital, PO Box 25427, Safat 13115, Kuwait

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Joze V. Trontelj MD, DSc,

Joze V. Trontelj MD, DSc

Institute of Clinical Neurophysiology, University Medical Center, Ljubljana, Slovenia

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Adnan J. Khuraibet MSc, DSc,

Adnan J. Khuraibet MSc, DSc

Department of Neurology and Clinical Neurophysiology, Ibn Sina Hospital, PO Box 25427, Safat 13115, Kuwait

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First published: 07 December 1998

https://doi.org/10.1002/(SICI)1097-4598(199810)21:10<1341::AID-MUS18>3.0.CO;2-4

Citations: 18

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Abstract

We report a 35-year-old patient with megaloblastic anemia who presented with features of subacute combined degeneration of the cord. Electrophysiological studies showed features of axonal neuropathy. In addition, there was evidence of prominent focal proximal conduction block in several nerves. After treatment with cyanocobalamin the neuropathy improved, and the peripheral nerve conduction block detected earlier disappeared. Reversible nerve conduction block as a feature of vitamin B12 deficiency in man, to our knowledge, has not been reported in literature, so far. © 1998 John-Wiley & Sons, Inc. Muscle Nerve 21:1341–1343, 1998.

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Volume21, Issue10

October 1998

Pages 1341-1343

Axonal and demyelinating neuropathy with reversible proximal conduction block, an unusual feature of vitamin B12 deficiency

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Axonal and demyelinating neuropathy with reversible proximal conduction block, an unusual feature of vitamin B12 deficiency

Abstract

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