Volume 21, Issue 10 pp. 1327-1330

Short Report

Relapses in the Guillain–Barré syndrome after treatment with intravenous immune globulin or plasma exchange

J.G. Romano MD,

J.G. Romano MD

Department of Neurology (D4-5), University of Miami School of Medicine, P.O. Box 016960, Miami, Florida 33101, USA

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F.T. Rotta MD,

F.T. Rotta MD

Department of Neurology (D4-5), University of Miami School of Medicine, P.O. Box 016960, Miami, Florida 33101, USA

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P. Potter MD,

P. Potter MD

Department of Neurology (D4-5), University of Miami School of Medicine, P.O. Box 016960, Miami, Florida 33101, USA

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V. Rosenfeld MD,

V. Rosenfeld MD

Department of Neurology (D4-5), University of Miami School of Medicine, P.O. Box 016960, Miami, Florida 33101, USA

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R. Santibanez MD,

R. Santibanez MD

Department of Neurology (D4-5), University of Miami School of Medicine, P.O. Box 016960, Miami, Florida 33101, USA

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B. Rocha MS,

B. Rocha MS

Department of Epidemiology, University of Miami School of Medicine, Miami, Florida, USA

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W.G. Bradley DM, FRCP,

Corresponding Author

W.G. Bradley DM, FRCP

Department of Neurology (D4-5), University of Miami School of Medicine, P.O. Box 016960, Miami, Florida 33101, USA

Department of Neurology (D4-5), University of Miami School of Medicine, P.O. Box 016960, Miami, Florida 33101, USASearch for more papers by this author

J.G. Romano MD,

J.G. Romano MD

Department of Neurology (D4-5), University of Miami School of Medicine, P.O. Box 016960, Miami, Florida 33101, USA

Search for more papers by this author

F.T. Rotta MD,

F.T. Rotta MD

Department of Neurology (D4-5), University of Miami School of Medicine, P.O. Box 016960, Miami, Florida 33101, USA

Search for more papers by this author

P. Potter MD,

P. Potter MD

Department of Neurology (D4-5), University of Miami School of Medicine, P.O. Box 016960, Miami, Florida 33101, USA

Search for more papers by this author

V. Rosenfeld MD,

V. Rosenfeld MD

Department of Neurology (D4-5), University of Miami School of Medicine, P.O. Box 016960, Miami, Florida 33101, USA

Search for more papers by this author

R. Santibanez MD,

R. Santibanez MD

Department of Neurology (D4-5), University of Miami School of Medicine, P.O. Box 016960, Miami, Florida 33101, USA

Search for more papers by this author

B. Rocha MS,

B. Rocha MS

Department of Epidemiology, University of Miami School of Medicine, Miami, Florida, USA

Search for more papers by this author

W.G. Bradley DM, FRCP,

Corresponding Author

W.G. Bradley DM, FRCP

Department of Neurology (D4-5), University of Miami School of Medicine, P.O. Box 016960, Miami, Florida 33101, USA

Department of Neurology (D4-5), University of Miami School of Medicine, P.O. Box 016960, Miami, Florida 33101, USASearch for more papers by this author

First published: 07 December 1998

https://doi.org/10.1002/(SICI)1097-4598(199810)21:10<1327::AID-MUS14>3.0.CO;2-Z

Citations: 13

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Abstract

To clarify the question of whether Guillain–Barré syndrome (GBS) patients treated with intravenous immune globulin (IVIG) relapse at a higher frequency than those treated with plasma exchange (PE), 54 patients with GBS were studied retrospectively. A higher frequency of relapses was noted in the PE-treated patients than in those receiving IVIG. The presence of an associated medical condition correlated with an increased risk of relapses, while earlier onset of treatment resulted in a decrease of relapses of GBS. This study found no support for prior suggestions of increased relapses in patients with GBS treated with IVIG as opposed to those treated with PE. © 1998 John Wiley & Sons, Inc. Muscle Nerve 21:1327–1330, 1998.

References

1 Asbury AK, Arnason BG, Adams RD: Criteria for diagnosis of Guillain-Barre syndrome. Ann Neurol 1978; 3: 565–566.
PubMed Google Scholar
2 Castro LHM, Ropper AH: Human immune globulin infusion in Guillain-Barre syndrome: worsenng during and after treatment. Neurology 1993; 43: 1034–1036.
10.1212/WNL.43.5.1034
CAS PubMed Web of Science® Google Scholar
3 Dutch Guillain-Barre Study Group: Treatment of Guillain-Barre syndrome with high dose immune globulns combined with methylprednisolone: a pilot study. Ann Neurol 1994; 35: 749–752.
10.1002/ana.410350618
PubMed Google Scholar
4 Guillain-Barre Syndrome Study Group: Plasmapheresis and acute Guillain-Barre syndrome. Neurology 1985; 35: 1096–1104.
10.1212/WNL.35.8.1096
PubMed Web of Science® Google Scholar
5 Hughes RAC, and the Plasma Exchange/Sandoglobulin Guillain-Barre Syndrome Trial Group, London, U.K.: Comparison of plasma exchange, intravenous immunoglobulin, and plasma exchange followed by intravenous immunoglobulin in the treatment of Guillain-Barre syndrome. Presented at the American Neurological Association meeting, October, 1996, Miami.
Google Scholar
6 Irani DN, Cornblath DR, Chaudhry V, Borel C, Hanley DF: Relapse in Guillain-Barre syndrome after treatment with human immune globulin. Neurology 1993; 43: 872–875.
10.1212/WNL.43.5.872
PubMed Web of Science® Google Scholar
7 Kennedy RH, Danielson MA, Mulder DW, Kurland LT: Guillain-Barre syndrome: a 42-year epidemiological and clinical study. Mayo Clin Proc 1978; 53: 93–99.
CAS PubMed Web of Science® Google Scholar
8 Kleyweg RP, van der Meche FGA: Treatment related fluctuations in Guillain-Barre syndrome after high-dose immunoglobulins or plasma-exchange. J Neurol Neurosurg Psychiatry 1991; 54: 957–960.
10.1136/jnnp.54.11.957
CAS PubMed Web of Science® Google Scholar
9 Loffel NB, Rossi LN, Mumenthaler M, Lutschg J, Ludin HP: The Landry-Guillain-Barre syndrome: complications, prognosis and natural history. J Neurol Sci 1977; 33: 71–79.
10.1016/0022-510X(77)90183-6
CAS PubMed Web of Science® Google Scholar
10 Plasma Exchange/Sandoglobulin Guillain-Barre Syndrome Trial Group: Randomised trial of plasma exchange, intravenous immunoglobulin, and combined treatment in Guillain-Barre syndrome. Lancet 1997; 349: 225–230.
PubMed Web of Science® Google Scholar
11 Pleasure DE, Lovelace RE, Duvoisin RC: The prognosis of acute polyradiculoneuritis. Neurology 1968; 18: 1143–1148.
10.1212/WNL.18.12.1143
CAS PubMed Web of Science® Google Scholar
12 Samantray SK, Johnson SC, Mathai KV, Pulimood BM: Landry-Guillain-Barre-Strohl Syndrome: a study of 302 cases. Med J Aust 1977; 2: 84–91.
10.5694/j.1326-5377.1977.tb99056.x
CAS PubMed Web of Science® Google Scholar
13 Tanaka M: Different mechanisms may operate in therapies for AIDP and multifocal motor neuropathy [letter]. Muscle Nerve 1994; 17: 1232–1233.
CAS PubMed Web of Science® Google Scholar
14 Van der Meche FGA, Schmitz PIM, and the Dutch Guillain-Barre Study Group: A randomized trial comparing intravenous immune globulin and plasma exchange in Guillain-Barre syndrome. N Engl J Med 1992; 326: 1123–1129.
10.1056/NEJM199204233261705
PubMed Web of Science® Google Scholar
15 Wijdicks EFM, Ropper AH: Acute relapsing Guillain-Barre syndrome after long asymptomatic intervals. Arch Neurol 1990; 47: 82–84.
10.1001/archneur.1990.00530010104027
CAS PubMed Web of Science® Google Scholar
16 Winer JB, Hughes RAC, Osmond C: A prospective study of acute idiopathic neuropathy. I. Clinical features and their prognostic value. J Neurol Neurosurg Psychiatry 1988; 51: 605–612.
10.1136/jnnp.51.5.605
CAS PubMed Web of Science® Google Scholar

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Volume21, Issue10

October 1998

Pages 1327-1330

Relapses in the Guillain–Barré syndrome after treatment with intravenous immune globulin or plasma exchange

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Relapses in the Guillain–Barré syndrome after treatment with intravenous immune globulin or plasma exchange

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